Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 506942Generated: October 27, 2026

3-Chloro-4-fluorophenylpiperazine → 3-{4-[4-(3-chloro-4-fluorophenyl)-piperazin-1-yl]-butyl}-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one monohydrochloride

https://huagongshe.com/reaction/506942

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloro-4-fluorophenylpiperazineHCID 2779263—
Reactant3-(4-Chlorobutyl)-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-oneHCID 68463623—
Product3-{4-[4-(3-chloro-4-fluorophenyl)-piperazin-1-yl]-butyl}-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one monohydrochlorideHCID 68465691—

Reaction Steps

The title compound is prepared according to process H by applying processing method 2 from 3-(4-chlorobutyl)-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one and 1-(3-chloro-4-fluorophenyl)-piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07786129B2
Source datasetuspto-grants-2010_08
ORD IDord-1d3aff0aa4f74032bb232d4e71ee78a2
Source noteuspto-grants-2010_08