HCID 59432345, compound → HCID 11548876, compound

Participants

Reaction Steps

Stir a mixture of (S)-[1-(2-Benzyloxy-ethyl)-7-methyl-8-trifluoromethyl-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl]-(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amine (0.420 g, 0.612 mmol) and 10% palladium on charcoal (0.210 g) in ethanol (50 mL) under a hydrogen balloon at room temperature for 3 h. Filter the mixture through Celite® and remove the solvents under reduced pressure to provide the title compound as a colorless foam (0.350 g, 97%). MS (ES+): 597 (M+H).

Provenance & Evidence