Trimethylsilyl isocyanate → HCID 59434054, compound

Participants

Reaction Steps

A mixture of N-(2-Amino-ethyl)-3-chloro-N-{2-[3-(3-chloro-2-methyl-phenyl)-4-oxo-imidazolidin-1-yl]-2-oxo-ethyl}-benzamide (80 mg, 0.16 mmol, 1 eq), Trimethylsilyl isocyanate (0.027 ml, 0.19 mmol, 1.2 eq), in THF (1 ml) was stirred at room temperature overnight. It was purified with HPLC to give the desired product. LCMS observed for (M+H)+: 492.1

Provenance & Evidence