HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 24863730, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1-Aminohomopiperidine | HCID 22198 | — |
| Reactant | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733207 | — |
| Reactant | HCID 24887408 | HCID 24887408 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 24863730 | HCID 24863730 | 52% |
Reaction Steps
Compound 3 was prepared analogously as described for compound 2 hereinabove from crude lithium 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylsulfanyl-1H-pyrazole-3-carboxylate, azepan-1-ylamine, TBTU and Et3N in DMF in 52% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07786144B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-1b53c562972741e2ac0b2176cb3f493d |
| Source note | uspto-grants-2010_08 |