Triethylamine → HCID 24863730, compound

HRID 507428Notes

Reaction equation

HRID 507428 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]([C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:14]=3[Cl:20])[N:11]=[C:10]([C:21]([O-])=[O:22])[C:9]=2[S:24][CH3:25])=[CH:4][CH:3]=1.[Li+].[N:27]1([NH2:34])[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]1.CN(C(ON1N=NC2C=CC=CC1=2)=[N+](C)C)C.[B-](F)(F)(F)F.CCN(CC)CC>CN(C=O)C>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]([C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:14]=3[Cl:20])[N:11]=[C:10]([C:21]([NH:34][N:27]3[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]3)=[O:22])[C:9]=2[S:24][CH3:25])=[CH:4][CH:3]=1

Participants

6

Reactant 4

HCID 8471TriethylamineHCID 221981-AminohomopiperidineHCID 2733207O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 24887408HCID 24887408, compound

Product 1

HCID 24863730HCID 24863730, compoundYield 52%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Compound 3 was prepared analogously as described for compound 2 hereinabove from crude lithium 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylsulfanyl-1H-pyrazole-3-carboxylate, azepan-1-ylamine, TBTU and Et3N in DMF in 52% yield.

Sources & evidence

ORD record
ord-1b53c562972741e2ac0b2176cb3f493d
Source dataset
uspto-grants-2010_08
Patent number
US07786144B2

Reaction notes

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