HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Bromo-2-fluorophenyl)acetonitrile → HCID 23509618, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Bromo-2-fluorophenyl)acetonitrile | HCID 7172308 | — |
| Reactant | (4,4-Dimethyl-2-oxo-1,4-dihydro-2H-3,1-benzoxazin-6-yl)boronic acid | HCID 10987806 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 23509618 | HCID 23509618 | — |
Reaction Steps
Prepared according to procedure B from 4-bromo-2-fluorophenylacetonitrile (T. Alessi A. H. P. U.S. Pat. No. 4,895,862) and (1,4-dihydro-4,4-dimethyl-2-oxo-2H-3,1-benzoxazin-6-yl)boronic acid. A grey solid; mp 253-256° C. 1H NMR (DMSO-d6) δ 10.35 (s, 1H) 7.67-7.49 (m, 5H), 6.97 (d, 1H, J=8.6 Hz) 4.09 (s, 2H) 1.67(s, 6H), MS [M−H]−m/z 309. Anal. Calc. For C18H15N2FO2.0.15 H2O: C, 69.07; H, 4.93; N, 8.95. Found C, 69.27; H 5.05; N, 8.50.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06713478B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-1d6ca9ec04454c4e87f2728c78f6a567 |
| Source note | uspto-grants-2004_03 |