Sodium sulfate decahydrate → HCID 23157654, compound

Participants

Reaction Steps

To a solution of methyl 5-(benzyloxy)-2′,6′-dimethylbiphenyl-3-carboxylate (1.04 g, 3.00 mmol) in tetrahydrofuran (10 mL) was added lithium aluminum hydride (0.114 g, 3.00 mmol) by small portions, and the mixture was stirred under a nitrogen atmosphere at room temperature for 2 hr. Sodium sulfate decahydrate (0.967 g, 3.00 mmol) was added to the reaction mixture, and the mixture was stirred at room temperature for 1 hr. The precipitated insoluble material was filtered off through celite, and the filtrate was concentrated under reduced pressure to give the title compound (0.934 g, yield 98%) as a colorless oil.

Provenance & Evidence