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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 508057Generated: November 3, 2026

Methanesulfonic Acid → HCID 86624378, compound

https://huagongshe.com/reaction/508057

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanesulfonic AcidHCID 6395—
ReactantHCID 23157445HCID 23157445—
SolventDiethyl EtherHCID 3283—
SolventEthyl AcetateHCID 8857—
ProductHCID 86624378HCID 8662437883.4%

Reaction Steps

To a solution of 3-[6-({[4′-(2-ethoxyethoxy)-2′,6′-dimethylbiphenyl-3-yl]methyl}amino)pyridin-3-yl]propanoic acid (0.729 g, 1.63 mmol) in diethyl ether (5 mL) and ethyl acetate (5 mL) was added methanesulfonic acid (0.157 g, 1.63 mmol), and the resulting crystals were washed with diethyl ether to give the title compound (0.740 g, yield 83%) as colorless crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07786165B2
Source datasetuspto-grants-2010_08
ORD IDord-bdfbaac1539b4025a3bc77a45e348583
Source noteuspto-grants-2010_08