Hydrogen chloride-ethyl acetate → HCID 68720671, compound

Participants

Reaction Steps

3-[4-({4-[(3,5-Diphenyl-1H-pyrazol-1-yl)methyl]-3-isopropoxybenzyl}amino)-2-fluorophenyl]propanoic acid (0.40 g, 0.71 mmol) was dissolved in ethyl acetate (4.0 mL), and 4 N hydrogen chloride/ethyl acetate solution (0.53 mL, 2.1 mmol) was added. The precipitated crystals were collected by filtration, washed with ethyl acetate and dried to give the title compound (0.41 g, yield 90%) as colorless crystals.

Provenance & Evidence