HCID 68278912, compound → HCID 68278953, compound

HRID 508187Notes

Reaction equation

HRID 508187 reaction equation
C([O:8][C:9]1[CH:18]=[CH:17][C:12]([C:13]([O:15][CH3:16])=[O:14])=[C:11]([C:19]([CH3:21])=[CH2:20])[CH:10]=1)C1C=CC=CC=1>CO.[Pd]>[OH:8][C:9]1[CH:18]=[CH:17][C:12]([C:13]([O:15][CH3:16])=[O:14])=[C:11]([CH:19]([CH3:21])[CH3:20])[CH:10]=1

Participants

4

Reactant 1

HCID 68278912HCID 68278912, compound

Product 1

HCID 68278953HCID 68278953, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

To a solution of methyl 4-(benzyloxy)-2-(prop-1-en-2-yl)benzoate (i-1d) (4.6 g, 16.3 mmol) in methanol (100 ml) was added Pd/C (0.46 g). The mixture was stirred at rt under H2 atmosphere for 24 h. Then the mixture was filtered, and the filtrate was concentrated to afford the title compound. LCMS (ESI) calc'd for C11H14O3 [M+H]+: 195.1. found: 195.1.

Workup

  1. filtrationThen the mixture was filtered
  2. concentrationthe filtrate was concentrated

Sources & evidence

ORD record
ord-1c5a44644fbd456bb94fb401d6c5abfa
Source dataset
uspto-grants-2015_08
Patent number
US09095583B2

Reaction notes

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