Sodium Hydroxide → HCID 68279051, compound

Participants

Reaction Steps

To a suspension of compound 26A (48 mg, 0.1 mmol) in H2O (20 mL) was added 0.1 M NaOH (1 mL), and the mixture was sonicated for ˜10 mins. The mixture was then dried under lyophilizaiton to give the title compound. LCMS (ESI) calc'd for C22H11ClF4N2NaO4 [M+H]+: 501. found: 501; 1H NMR (400 MHz, MeOD) δ 8.45 (1H, d, J=8.0), 7.91-7.76 (5H, m), 7.31 (1H, q, J=8.0 Hz), 7.20-7.17 (2H, m).

Provenance & Evidence