HCID 11222461, compound → HCID 52951615, compound

HRID 508605Notes

Reaction equation

HRID 508605 reaction equation
C([O:3][C:4]([C:6]1[CH:10]=[C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[N:8]([C:17]2[CH:22]=[CH:21][C:20]([S:23]([CH3:26])(=[O:25])=[O:24])=[CH:19][CH:18]=2)[N:7]=1)=O)C.C(C1C=C(C2C=CC=CC=2)N(C2C=CC(S(N)(=O)=O)=CC=2)N=1)=O>>[CH3:26][S:23]([C:20]1[CH:19]=[CH:18][C:17]([N:8]2[C:9]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)=[CH:10][C:6]([CH:4]=[O:3])=[N:7]2)=[CH:22][CH:21]=1)(=[O:24])=[O:25]

Participants

3

Reactant 2

HCID 11222461HCID 11222461, compoundHCID 12082818HCID 12082818, compound

Product 1

HCID 52951615HCID 52951615, compoundYield 65%

Procedure

The titled compound was prepared in 65% yield from the compound 3a using the procedure detailed for compound 12b. mp 133.0-135.5° C. 1H NMR (300 MHz, DMSO-d6): δ 10.03 (s, 1H), 8.02 (d, J=9 Hz, 2H), 7.63 (d, J=9 Hz, 2H), 7.47-7.39 (m, 3H), 7.37-7.29 (m, 2H), 7.22 (s, 1H), 3.29 (s, 3H).

Sources & evidence

ORD record
ord-fe75426ddf3749f48fd69dfcd06c738c
Source dataset
uspto-grants-2015_08
Patent number
US09096532B2

Reaction notes

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