Hydrochloric Acid → HCID 86658632, compound

Participants

Reaction Steps

To a solution of 4-[4-methoxy-2-oxo-3-(2,4,6-trimethyl-phenyl)-cyclopent-3-enylmethyl]-piperidine-1-carboxylic acid tert-butyl ester (15.4 g, 36 mmol) in acetone (100 ml) is added 2N HCl (100 ml) and the reaction heated to reflux for 4 hours. The solvent is removed under reduced pressure to give 4-[2,4-dioxo-3-(2,4,6-trimethyl-phenyl)-cyclopentylmethyl]-piperidinium hydrochloride (12.58 g)

Provenance & Evidence