Methanol → HCID 57779708, compound

HRID 509204Notes

Reaction equation

HRID 509204 reaction equation
[CH3:1][O:2][C:3](=[O:27])[CH:4]([CH:11]1[CH2:16][CH2:15][N:14](C(OCC2C=CC=CC=2)=O)[CH2:13][CH2:12]1)[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.CO>CCO>[C:5]1([CH:4]([CH:11]2[CH2:16][CH2:15][NH:14][CH2:13][CH2:12]2)[C:3]([O:2][CH3:1])=[O:27])[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=1

Participants

4

Reactant 2

HCID 887MethanolHCID 57779521HCID 57779521, compound

Product 1

HCID 57779708HCID 57779708, compoundYield 99%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Following the same procedure as described in Example 10, step 1, but substituting 2-nitro-4-(thiophen-2-yl)aniline for compound 91, and MeOH for EtOH, the title compound 92 (0.384 g, 99%) was obtained as a colorless oil. LRMS (ESI): (calc) 233.31 (found) 234.14 (MH)+

Sources & evidence

ORD record
ord-61eca603e397404693d67e1e73245167
Source dataset
uspto-grants-2015_08
Patent number
US09096565B2

Reaction notes

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