HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenylpiperazine → HCID 57779639, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenylpiperazine | HCID 7096 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Chloropyrimidine | HCID 74404 | — |
| Reactant | HCID 57779708 | HCID 57779708 | — |
| Catalyst | HCID 178454919 | HCID 178454919 | — |
| Solvent | Benzene | HCID 241 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 57779639 | HCID 57779639 | 78% |
Reaction Steps
Following the same procedure as described in Example 15 (Scheme 15), step 1, but substituting compound 54 for 2-chloropyrimidine, compound 62 for compound 92, Cs2CO3/Pd(PtBu3)2 for potassium carbonate and benzene for DMSO, the title compound 93 (0.232 g, 78%) was obtained as a white solid. LRMS (ESI): (calc) 311.38 (found) 312.32 (MH)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09096565B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-0dab88dbfa0544acb5e167c3036ef2d7 |
| Source note | uspto-grants-2015_08 |