HRID509205

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7096

Phenylpiperazine

C10H14N2

HCID11430

Potassium Carbonate

CK2O3

HCID74404

2-Chloropyrimidine

C4H3ClN2

HCID57779708

未命名化合物

PRODUCTS

生成物

HCID57779639

未命名化合物

收率 78%

AUXILIARIES

试剂、催化剂与溶剂

结构：CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C.O=C([O-])[O-].[Cs+].[Cs+]

催化剂HCID178454919

未命名化合物

溶剂HCID241

Benzene

C6H6

溶剂HCID679

Dimethyl sulfoxide

C2H6OS

PROCEDURE

实验过程

Following the same procedure as described in Example 15 (Scheme 15), step 1, but substituting compound 54 for 2-chloropyrimidine, compound 62 for compound 92, Cs2CO3/Pd(PtBu3)2 for potassium carbonate and benzene for DMSO, the title compound 93 (0.232 g, 78%) was obtained as a white solid. LRMS (ESI): (calc) 311.38 (found) 312.32 (MH)+