HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-4-nitrobenzamide → 4-Amino-2-methylbenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-4-nitrobenzamide | HCID 20165120 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Palladium | HCID 23938 | — |
| Product | 4-Amino-2-methylbenzamide | HCID 23068206 | — |
Reaction Steps
2-methyl-4-nitrobenzamide (E111) was dissolved in EtOH under Ar and 10% Pd/C added. The reaction was pump-purged with H2 and left stirring at room temperature overnight. The catalyst was removed by filtration and the reaction concentrated to give pure 4-amino-2-methylbenzamide (E112).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09096569B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-06ba7f3e260f4486ae4d8df298d68d37 |
| Source note | uspto-grants-2015_08 |