2-Nitro-4-(trifluoromethoxy)aniline → (E)-1-(2-Pyridyl)-2-styryl-5-trifluoromethoxy-1H-benzimidazole

참여 물질

반응 단계

The titled compound was prepared from 2-nitro4-trifluoromethoxyaniline according to the preparation of (E)-1-(2-pyridyl)-2-styryl-5-trifluoromethyl-1H-benzimidazole (Example 57). MW: 381.36; mp: 92.0-93.0° C.; 1H-NMR (CDCl3) δ: 8.81-8.77 (1H, m), 8.02 (1H, d, J=16.5 Hz), 8.05-7.98 (1H, m), 7.71-7.68 (1H, m), 7.54-7.45 (4H, m), 7.45 (1H, d, J=8.8 Hz), 7.42-7.30 (3H, m), 7.17-7.10 (1H, m), 7.10 (1H, d, J=16.1 Hz)

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