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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 509621Generated: October 30, 2026

HCID 178418361, compound → HCID 178423880, compound

https://huagongshe.com/reaction/509621

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178418361HCID 178418361—
ReactantHCID 178423879HCID 178423879—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 178423880HCID 17842388030%

Reaction Steps

To a solution of 5-Methyl-2-{(E)-2-[4-(5-methyl-furan-2-yl)-1H-imidazol-2-yl]-vinyl}-[1,2,4]triazolo[1,5-a]pyridine (20 mg, 0.07 mmol) in methanol (20 mL) was added 10% palladium on carbon (20 mg). The reaction was shaken under 3 bar atmosphere of hydrogen overnight. Filtration and evaporation of the volatiles afforded the title compound (6 mg, 30%). LC-MS: m/z=308.3 (MH+), tR=0.41 minutes, method A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09096589B2
Source datasetuspto-grants-2015_08
ORD IDord-b8d4af0057d44057b4283904cee09b6f
Source noteuspto-grants-2015_08