HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178418361, compound → HCID 178423880, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Reactant | HCID 178423879 | HCID 178423879 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178423880 | HCID 178423880 | 30% |
Reaction Steps
To a solution of 5-Methyl-2-{(E)-2-[4-(5-methyl-furan-2-yl)-1H-imidazol-2-yl]-vinyl}-[1,2,4]triazolo[1,5-a]pyridine (20 mg, 0.07 mmol) in methanol (20 mL) was added 10% palladium on carbon (20 mg). The reaction was shaken under 3 bar atmosphere of hydrogen overnight. Filtration and evaporation of the volatiles afforded the title compound (6 mg, 30%). LC-MS: m/z=308.3 (MH+), tR=0.41 minutes, method A.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09096589B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-b8d4af0057d44057b4283904cee09b6f |
| Source note | uspto-grants-2015_08 |