反应详情

温度

220 °C

246 mg (0.629 mmol) of the compound from example 48A were initially charged in N,N-dimethylacetamide (22 ml) and stirred in a microwave at 220° C. for 30 min. The reaction mixture was poured onto ice-water and filtered. The filter residue was washed with water and dried under high vacuum at 50° C. overnight. This gave 142 mg (57% of theory) of the title compound in solid form.

1. additionThe reaction mixture was poured onto ice-water
2. filtrationfiltered
3. washThe filter residue was washed with water
4. customdried under high vacuum at 50° C. overnight