HRID510231

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID66827

Boronic acid, phenyl-

C6H7BO2

反应SMILES：CC1(C)OB(c2ccnn2C2CCCCO2)OC1(C)C

HCID11587208

1-(Oxan-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

C14H23BN2O3

反应SMILES：FC(F)(F)c1nc(Cl)c2c(n1)CN(Cc1ccccc1)CC2

HCID18456521

7-Benzyl-4-chloro-2-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine

C15H13ClF3N3

PRODUCTS

产物

反应SMILES：FC(F)(F)c1nc2c(c(-c3ccnn3C3CCCCO3)n1)CCN(Cc1ccccc1)C2

HCID90407337

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in a manner analogous to Intermediate 12 substituting 7-benzyl-4-chloro-2-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine for Intermediate 11 and 1-(tetrahydropyran-2-yl)-1 h-pyrazole-5-boronic acid pinacol ester for phenylboronic acid. MS (ESI): mass calcd. for C23H24F3N5O, 443.2. m/z found, 444.2 [M+H]+.