Morpholine → HCID 777806, compound

HRID 510476Notes

Reaction equation

[CH3:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[N+:11]([O-:13])=[O:12])[C:5]([OH:7])=O.[NH:14]1[CH2:19][CH2:18][O:17][CH2:16][CH2:15]1>>[CH3:1][C:2]1[CH:3]=[C:4]([C:5]([N:14]2[CH2:19][CH2:18][O:17][CH2:16][CH2:15]2)=[O:7])[CH:8]=[CH:9][C:10]=1[N+:11]([O-:13])=[O:12]

Participants

Reactant 2

HCID 8083Morpholine

HCID 183703-Methyl-4-nitrobenzoic acid

Product 1

HCID 777806HCID 777806, compound

Procedure

Prepared from 3-methyl-4-nitrobenzoic acid and morpholine following the method used to prepare Intermediate 29. δH (DMSO-d6) 8.03 (d, J=8.3 Hz, 1H), 7.60-7.52 (m, 1H), 7.47 (dd, J8.4, 1.9 Hz, 1H), 3.50-3.70 (m, 6H), 3.28 (m, 2H), 2.53 (s, 3H).

Sources & evidence

ORD record: ord-eb148a5a43cf4f058d199227637f89c0
Source dataset: uspto-grants-2015_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09096614B2

Reaction notes

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