HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 7-(3-(2-Chloro-4-(2,2,2-trifluoroethoxy)phenoxy)propoxy)-2-methylchromane-2-carboxylic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Ethyl 7-(3-(2-chloro-4-(2,2,2-trifluoroethoxy)phenoxy)propoxy)-chromane-2-carboxylate | HCID 22737360 | — |
| Product | 7-(3-(2-Chloro-4-(2,2,2-trifluoroethoxy)phenoxy)propoxy)-2-methylchromane-2-carboxylic Acid | HCID 10140333 | — |
Reaction Steps
The title compound was prepared from ethyl 7-(3-(2-chloro-4-(2,2,2-trifluoroethoxy)phenoxy)propoxy)-chromane-2-carboxylate (Example 5, Step D) following the procedure described in Example 1, Step C employing iodomethane instead of iodoethane followed by hydrolysis as described in Example 5, Step E.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06713508B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-c892b6ffb31a4379bd07c1ee78c692ef |
| Source note | uspto-grants-2004_03 |