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HRID5109

反应详情

EQUATION

反应方程式

HRID 5109 的结构方程式

REACTANTS

反应物

2
结构：COS(=O)(=O)F
HCID9870

Fluorosulfuric acid, methyl ester

CH3FO3S

结构：COc1ccc(CSC[C@@H]2CCCN2C)cc1
HCID57048351

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(CSC[C@@H]2CCC[N+]2(C)C)cc1.O=S(=O)([O-])F
HCID14880299

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

The procedure described in Preparation 5-(5) was repeated, but using 740 mg of (2S)-2-(4-methoxybenzylthiomethyl)-1-methylpyrrolidine and 243 μl of methyl fluorosulfonate in the presence of 22 ml of methylene chloride, to afford 1.0 g of the title compound as crystals, melting at 150°-153° C.

WORKUP

后处理

  1. customThe procedure described in Preparation 5-(5)