Trifluoroacetic acid → HCID 67254982, compound

Participants

Reaction Steps

To tert-butyl [2-methyl-3-oxo-7-(pyrrolidin-1-ylmethyl)-2,3-dihydro-1H-isoindol-4-yl]carbamate (Compound 109B) was added DCM (0.5 mL) and TFA (0.5 mL, 6 mmol). The solution was stirred at room temperature for 20 minutes. The crude product was dried in vacuo and used directly in next step without further purification. MS (ES+): m/z 246.31 (100) [MH+]; HPLC: tR=0.29 min (UPLC, Analytical).

Provenance & Evidence