HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Chloromethyl)-2-fluoro-3-methoxy-4-nitrobenzene → Diethyl (2-fluoro-3-methoxy-4-nitrobenzyl)phosphonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Chloromethyl)-2-fluoro-3-methoxy-4-nitrobenzene | HCID 67254948 | — |
| Reactant | Diethyl 3-chloro-4-nitrobenzylphosphonate | HCID 86654007 | — |
| Product | Diethyl (2-fluoro-3-methoxy-4-nitrobenzyl)phosphonate | HCID 86654025 | — |
Reaction Steps
The title compound was prepared using the procedure from Compound 104C (Diethyl (3-chloro-4-nitrobenzyl)phosphonate) with 1-(chloromethyl)-2-fluoro-3-methoxy-4-nitrobenzene (Compound 147C). 1H NMR (CDCl3, 400 MHz): δ=1.28-1.32 (m, 6 H), 3.19-3.31 (m, 2 H), 7.14-7.22 (m, 1 H), 7.54-7.61 (m, 1 H). MS (ES+): m/z 322.08 [MH+] (TOF, polar).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09096624B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-44f8e5b6c0084360ab0d823d74eb645a |
| Source note | uspto-grants-2015_08 |