HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Fluoro-3-methoxy-4-nitrophenyl)methanol → 1-(Chloromethyl)-2-fluoro-3-methoxy-4-nitrobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Fluoro-3-methoxy-4-nitrophenyl)methanol | HCID 67254223 | — |
| Reactant | 1-(Chloromethyl)-2-fluoro-5-methoxy-4-nitrobenzene | HCID 67255107 | — |
| Product | 1-(Chloromethyl)-2-fluoro-3-methoxy-4-nitrobenzene | HCID 67254948 | — |
Reaction Steps
The title compound was prepared using the procedure from Compound 130C (1-(chloromethyl)-2-fluoro-5-methoxy-4-nitrobenzene) with (2-fluoro-3-methoxy-4-nitrophenyl)methanol (Compound 147D). 1H NMR (CDCl3, 400 MHz): δ=4.10 (d, J=1.77 Hz, 3 H), 4.64 (d, J=1.52 Hz, 2 H), 7.62 (dd, J=8.59, 1.77 Hz, 1 H). MS (ES+): m/z 220.00 [MH+] (TOF, polar).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09096624B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-835ddf2f62bc4739a4f4549b5baf9233 |
| Source note | uspto-grants-2015_08 |