HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → HCID 58293049, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | Potassium Phosphate, Tribasic | HCID 62657 | — |
| Reactant | Thiomorpholine 1,1-dioxide | HCID 6484228 | — |
| Reactant | Diethyl [4-({4-[(7-bromo-2-methyl-3-oxo-2,3-dihydro-1H-isoindol-4-yl)amino]-5(trifluoromethyl)pyrimidin-2-yl}amino)benzyl]phosphonate | HCID 58292897 | — |
| Product | HCID 58293049 | HCID 58293049 | — |
Reaction Steps
The title compound was prepared according to the procedure for Example 199 using Diethyl [4-({4-[(7-bromo-2-methyl-3-oxo-2,3-dihydro-1H-isoindol-4-yl)amino]-5(trifluoromethyl)pyrimidin-2-yl}amino)benzyl]phosphonate and thiomorpholine-1,1-dioxide and replacing Cs2CO3, with K3PO4. MS (ES+): m/z 683.25 (100) [MH+]; HPLC: tR=0.98 min (UPLC, purity).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09096624B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-5dc13b4f6ca8411d8a10d2a8321b4db6 |
| Source note | uspto-grants-2015_08 |