反应详情

Methyl 3-(2-methyl-6-nitrophenyl)propenoate (0.24 g, 1.1 mmol) was dissolved in triethylphosphite (1 mL) and heated under reflux for 20 h. The solvent was removed in vacuo and the crude product was purified by silica gel chromatography (EtOAc:hexane=8:92) to give 0.15 g (71% yield) of the title compound as a pale yellow solid:

1. temperatureheated
2. temperatureunder reflux for 20 h
3. customThe solvent was removed in vacuo
4. customthe crude product was purified by silica gel chromatography (EtOAc:hexane=8:92)