Thionyl Chloride → HCID 86675010, compound

HRID 511920Notes

Reaction equation

HRID 511920 reaction equation
[CH:1]([O:4][C:5]([O:7][C:8]1[CH:16]=[CH:15][CH:14]=[CH:13][C:9]=1[C:10](O)=[O:11])=[O:6])([CH3:3])[CH3:2].S(Cl)([Cl:19])=O>ClCCl.N1C=CC=CC=1>[CH:1]([O:4][C:5]([O:7][C:8]1[CH:16]=[CH:15][CH:14]=[CH:13][C:9]=1[C:10]([Cl:19])=[O:11])=[O:6])([CH3:3])[CH3:2]

Participants

5

Reactant 2

HCID 24386Thionyl ChlorideHCID 67209003HCID 67209003, compound

Product 1

HCID 86675010HCID 86675010, compoundYield 106.8%

Reagents, catalysts & solvents 2

HCID 1049PyridineCatalystHCID 6344DichloromethaneSolvent

Procedure

5 g (22 mmol) of 2-(isopropoxycarbonyloxy)benzoic acid are dissolved in 50 ml of dichloromethane with a few drops of pyridine. 1.95 ml (27 mmol) of thionyl chloride are added dropwise and the mixture is stirred at ambient temperature for 18 h and then concentrated to dryness. 5.7 g of 2-(isopropoxycarbonyloxy)benzoyl chloride are obtained with a quantitative yield.

Workup

  1. concentrationconcentrated to dryness

Sources & evidence

ORD record
ord-aeef175910b24d7692b17f71965d9d91
Source dataset
uspto-grants-2015_08
Patent number
US09102607B2

Reaction notes

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