Boron tribromide → HCID 66930869, compound

HRID 511962Notes

Reaction equation

HRID 511962 reaction equation
C[O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]OC1C=CC=CC=1.B(Br)(Br)[Br:24]>C(Cl)Cl>[Br:24][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=1[OH:2]

Participants

4

Reactant 2

HCID 25134Boron tribromideHCID 66931163HCID 66931163, compound

Product 1

HCID 66930869HCID 66930869, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

7-Bromo-1-(2-hydroxy-phenyl)-heptane (9.3) was synthesized as in 9.1 using 8.3 (0.30 g, 1.01 mmol) in anhydrous CH2Cl2 (10 mL), and BBr3 (1M solution in CH2Cl2, 2.2 mL, 2.2 mmol). The title compound (9.3) was isolated as a viscous liquid after purification by flash column chromatography (0.247 g, 90% yield).

Sources & evidence

ORD record
ord-eb64d0b098fe413babe51c74fbbdbdc3
Source dataset
uspto-grants-2015_08
Patent number
US09102622B2

Reaction notes

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