反应详情

A mixture of 70 (2.75 g, 15.3 mmol) in methanol (50 mL) and hydrazine hydrate (65% in water, 2.3 g, 30 mmol) was heated under reflux for 3 h. The reaction mixture was concentrated under reduced pressure and the residue was diluted with benzene. The solvent was evaporated and the crude product was further dried under high vacuum (6 h) to give 71 (2.75 g), as a light yellow waxy material, which was used in the next step without further purification.

1. temperaturewas heated
2. temperatureunder reflux for 3 h
3. concentrationThe reaction mixture was concentrated under reduced pressure
4. additionthe residue was diluted with benzene
5. customThe solvent was evaporated
6. dry with materialthe crude product was further dried under high vacuum (6 h)