3-Methoxybenzaldehyde → HCID 57999445, compound

HRID 512012Notes

Reaction equation

HRID 512012 reaction equation
C(OC1C=C([C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([CH:21]([C:23]3[O:24][C:25]([CH3:28])=[N:26][N:27]=3)[OH:22])[CH:16]=2)C=CC=1)C1C=CC=CC=1.C(=O)C1C=CC=[C:32]([O:36]C)C=1.CN1NC=CO1>>[CH3:32][O:36][C:15]1[CH:16]=[C:17]([CH:21]([C:23]2[O:24][C:25]([CH3:28])=[N:26][N:27]=2)[OH:22])[CH:18]=[CH:19][CH:20]=1

Participants

4

Reactant 3

HCID 115693-MethoxybenzaldehydeHCID 20213174HCID 20213174, compoundHCID 57999483HCID 57999483, compound

Product 1

HCID 57999445HCID 57999445, compoundYield 53.4%

Procedure

The synthesis was carried out analogous to the preparation of 77 using 79 (0.14 g, 1.03 mmol) and 63 (0.29 g, 3.45 mmol). Purification by flash column chromatography on silica gel gave compound 80 (0.12 g, 53.4% yield) as a viscous liquid.

Workup

  1. customPurification by flash column chromatography on silica gel

Sources & evidence

ORD record
ord-59f3b3b1bd3b4b45b531443ffc6d761e
Source dataset
uspto-grants-2015_08
Patent number
US09102622B2

Reaction notes

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