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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 512218Generated: November 4, 2026

2-Chloro-5-methylbenzoic Acid → 2-Chloro-5-methyl-N-(1-methyl-4-phenyl-piperidin-4-ylmethyl)-benzamide

https://huagongshe.com/reaction/512218

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-methylbenzoic AcidHCID 240430—
Reactant(1-Methyl-4-phenylpiperidin-4-yl)methanamineHCID 343885—
Product2-Chloro-5-methyl-N-(1-methyl-4-phenyl-piperidin-4-ylmethyl)-benzamideHCID 86716251—

Reaction Steps

From 2-chloro-5-methylbenzoic acid and C-(1-methyl-4-phenyl-piperidin-4-yl)-methylamine. LCMS (MH+): m/z=367.0, tR (minutes, Method A)=0.68

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09102591B2
Source datasetuspto-grants-2015_08
ORD IDord-40dd52f5c4c4449a9262230e19477e29
Source noteuspto-grants-2015_08