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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 512224Generated: October 27, 2026

2-Chloro-5-methylbenzoic Acid → 2-Chloro-5-methyl-N-[4-(6-methyl-pyridin-3-yl)-tetrahydro-pyran-4-ylmethyl]-benzamide

https://huagongshe.com/reaction/512224

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-methylbenzoic AcidHCID 240430—
ReactantC-[4-(6-methylpyridin-3-yl)-tetrahydropyran-4-yl]methylamineHCID 86716258—
Product2-Chloro-5-methyl-N-[4-(6-methyl-pyridin-3-yl)-tetrahydro-pyran-4-ylmethyl]-benzamideHCID 86716257—

Reaction Steps

From 2-chloro-5-methylbenzoic acid and C-[4-(6-methylpyridin-3-yl)-tetrahydropyran-4-yl]methylamine. LCMS (MH+): m/z=359.0, tR (minutes, Method B)=0.74

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09102591B2
Source datasetuspto-grants-2015_08
ORD IDord-915f77ae638b47e38a0940c7e9234d0e
Source noteuspto-grants-2015_08