2-Chlorobenzoic Acid → HCID 86716307, compound

HRID 512262Notes

Reaction equation

HRID 512262 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[CH:11]1([C:14]2[N:19]=[CH:18][C:17]([CH:20]([CH2:23][C:24]3([C:27]([F:30])([F:29])[F:28])[CH2:26][CH2:25]3)[CH2:21][NH2:22])=[CH:16][CH:15]=2)[CH2:13][CH2:12]1>>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:22][CH2:21][CH:20]([C:17]1[CH:18]=[N:19][C:14]([CH:11]2[CH2:12][CH2:13]2)=[CH:15][CH:16]=1)[CH2:23][C:24]1([C:27]([F:28])([F:29])[F:30])[CH2:26][CH2:25]1)=[O:6]

Participants

3

Reactant 2

HCID 83742-Chlorobenzoic AcidHCID 86716302HCID 86716302, compound

Product 1

HCID 86716307HCID 86716307, compound

Procedure

From 2-chlorobenzoic acid and 2-(6-cyclopropyl-pyridin-3-yl)-3-(1-trifluoromethyl-cyclopropyl)-propylamine. LCMS (MH+): m/z=423.1, tR (minutes, Method G)=2.04

Sources & evidence

ORD record
ord-45ba1026c8c445618f1dcd4bd87011b3
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

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