2-Chlorobenzoic Acid → HCID 86716311, compound

HRID 512268Notes

Reaction equation

HRID 512268 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[F:11][C:12]1([F:27])[CH2:17][CH2:16][C:15]([CH2:25][NH2:26])([C:18]2[CH:19]=[N:20][C:21]([CH3:24])=[N:22][CH:23]=2)[CH2:14][CH2:13]1>>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:26][CH2:25][C:15]1([C:18]2[CH:23]=[N:22][C:21]([CH3:24])=[N:20][CH:19]=2)[CH2:16][CH2:17][C:12]([F:11])([F:27])[CH2:13][CH2:14]1)=[O:6]

Participants

3

Reactant 2

HCID 83742-Chlorobenzoic AcidHCID 86716312HCID 86716312, compound

Product 1

HCID 86716311HCID 86716311, compound

Procedure

From 2-chlorobenzoic acid and C-[4,4-difluoro-1-(2-methyl-pyrimidin-5-yl)-cyclohexyl]-methylamine. LCMS (MH+): m/z=380.1, tR (minutes, Method F)=2.37

Sources & evidence

ORD record
ord-8c83de2037de415da2f0c9b58bf89dc2
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

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