2-Chlorobenzoic Acid → HCID 86716321, compound

HRID 512277Notes

Reaction equation

HRID 512277 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[CH:11]1([CH2:14][CH:15]([C:18]2[CH:19]=[N:20][C:21]([F:24])=[CH:22][CH:23]=2)[CH2:16][NH2:17])[CH2:13][CH2:12]1>>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:17][CH2:16][CH:15]([C:18]1[CH:19]=[N:20][C:21]([F:24])=[CH:22][CH:23]=1)[CH2:14][CH:11]1[CH2:12][CH2:13]1)=[O:6]

Participants

3

Reactant 2

HCID 83742-Chlorobenzoic AcidHCID 86716322HCID 86716322, compound

Product 1

HCID 86716321HCID 86716321, compound

Procedure

From 2-chlorobenzoic acid and 3-cyclopropyl-2-(6-fluoropyridin-3-yl)propan-1-amine. LCMS (MH+): m/z=333.1, tR (minutes, Method F)=2.43

Sources & evidence

ORD record
ord-1e2865b44fab473ab5a521b24105295c
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

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