2-Chlorobenzoic Acid → HCID 86716363, compound

HRID 512314Notes

Reaction equation

HRID 512314 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[F:11][C:12]1([F:28])[CH2:17][CH2:16][CH:15]([CH:18]([C:21]2[CH:22]=[N:23][C:24]([CH3:27])=[N:25][CH:26]=2)[CH2:19][NH2:20])[CH2:14][CH2:13]1>>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:20][CH2:19][CH:18]([CH:15]1[CH2:16][CH2:17][C:12]([F:28])([F:11])[CH2:13][CH2:14]1)[C:21]1[CH:22]=[N:23][C:24]([CH3:27])=[N:25][CH:26]=1)=[O:6]

Participants

3

Reactant 2

HCID 83742-Chlorobenzoic AcidHCID 86716362HCID 86716362, compound

Product 1

HCID 86716363HCID 86716363, compound

Procedure

From 2-chlorobenzoic acid and 2-(4,4-difluorocyclohexyl)-2-(2-methylpyrimidin-5-yl)ethanamine. LCMS (MH+): m/z=394.1, tR (minutes, Method F)=2.1

Sources & evidence

ORD record
ord-ee7aacb53c5742c5b45f22704f37a8b7
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

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