2-Chlorobenzoic Acid → HCID 86716380, compound

HRID 512330Notes

Reaction equation

HRID 512330 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[N:11]1[CH:16]=[CH:15][C:14]([CH:17]([C:20]2[CH:21]=[N:22][C:23]([C:26]([F:29])([F:28])[F:27])=[N:24][CH:25]=2)[CH2:18][NH2:19])=[CH:13][CH:12]=1>>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:19][CH2:18][CH:17]([C:14]1[CH:15]=[CH:16][N:11]=[CH:12][CH:13]=1)[C:20]1[CH:21]=[N:22][C:23]([C:26]([F:28])([F:29])[F:27])=[N:24][CH:25]=1)=[O:6]

Participants

3

Reactant 2

HCID 83742-Chlorobenzoic AcidHCID 86716381HCID 86716381, compound

Product 1

HCID 86716380HCID 86716380, compound

Procedure

From 2-chlorobenzoic acid and 2-(pyridin-4-yl)-2-(2-(trifluoromethyl)pyrimidin-5-yl)ethanamine. LCMS (MH+): m/z=407.1, tR (minutes, Method F)=2.25

Sources & evidence

ORD record
ord-c12ad50565894722936eb7efc0914ca4
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

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