2-Chlorobenzoic Acid → HCID 86716439, compound

HRID 512382Notes

Reaction equation

HRID 512382 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[F:11][C:12]1([F:30])[CH2:17][CH2:16][C:15]([CH2:28][NH2:29])([C:18]2[CH:19]=[N:20][C:21]([C:24]([F:27])([F:26])[F:25])=[N:22][CH:23]=2)[CH2:14][CH2:13]1>>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:29][CH2:28][C:15]1([C:18]2[CH:19]=[N:20][C:21]([C:24]([F:27])([F:26])[F:25])=[N:22][CH:23]=2)[CH2:16][CH2:17][C:12]([F:11])([F:30])[CH2:13][CH2:14]1)=[O:6]

Participants

3

Reactant 2

HCID 83742-Chlorobenzoic AcidHCID 86716351(4,4-Difluoro-1-(2-(trifluoromethyl)pyrimidin-5-yl)cyclohexyl)methanamine

Product 1

HCID 86716439HCID 86716439, compound

Procedure

From 2-chlorobenzoic acid and [4,4-Difluoro-1-(2-(trifluoromethyl)pyrimidin-5-yl)cyclohexyl]methanamine. LCMS (MH+): m/z=434.1, tR (minutes, Method F)=3.04

Sources & evidence

ORD record
ord-097724b1a54a48ac95f8aab4545c80dc
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

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