反应详情

The racemic mixture which was prepared in a similar manner to example 3a from 2-chloro-3-methoxybenzoic acid and 3-cyclopropyl-2-(6-trifluoromethyl-pyridin-3-yl)-propylamine was separated into the two enantiomers by preparative SFC to yield the title compound. LCMS (MH+): m/z=413.1, tR (minutes, Method G)=2.84. [α]D20=+20.9 (c=0.86 mg/mL,CHCl3)

1. customwas separated into the two enantiomers by preparative SFC