反应详情

The racemic mixture which was prepared in a similar manner to example 3a from 2-chloro-3-methoxybenzoic acid and 3-cyclopropyl-2-(6-(difluoromethyl)pyridin-3-yl)propan-1-amine was separated into the two enantiomers by preparative SFC to yield the title compound. LCMS (MH+): m/z=395.1, tR (minutes, Method F)=2.96. [α]D20=+28.21 (c=2.80 mg/mL,CHCl3)

1. customwas separated into the two enantiomers by preparative SFC