Hydrochloric Acid → HCID 59828247, compound

Participants

Reaction Steps

At room temperature, 160 mg (0.56 mmol) of ethyl 2-oxo-6-(pentafluoroethyl)-1,2-dihydropyridine-3-carboxylate were stirred in 5 ml of 2-butylamine for 14 h. The pH was then adjusted to 2 by addition of 1N hydrochloric acid, which resulted in the precipitation of a colorless solid. Filtration with suction and drying gave 160 mg (91% of theory) of the product.

Provenance & Evidence