Hydrochloric Acid → HCID 59828242, compound

Participants

Reaction Steps

250 mg (0.78 mmol) of methyl 6-(heptafluoropropyl)-2-oxo-1,2-dihydropyridine-3-carboxylate in 5 ml of propylamine were heated under reflux for 5 h. The mixture was then adjusted to pH 2 by addition of 1N hydrochloric acid and extracted with dichloromethane. Drying and concentration gave 240 mg (88% of theory) of a beige powder.

Provenance & Evidence