反应详情

0.53 g (22.8 mmol) of sodium were dissolved in 50 ml of methanol, 5.0 g (19.0 mmol) of 1-butoxy-5-chloro-4,4,5,5-tetrafluoropent-1-en-3-one and 2.0 g (19.0 mmol) of malonamide were then added and the mixture was heated under reflux for 6 h. The mixture was concentrated, and 1N hydrochloric acid was then added. The resulting precipitate was filtered off with suction and dried. This gave 3.8 g (73% of theory) of a brownish powder.

1. temperaturethe mixture was heated
2. temperatureunder reflux for 6 h
3. concentrationThe mixture was concentrated
4. addition1N hydrochloric acid was then added
5. filtrationThe resulting precipitate was filtered off with suction
6. customdried