反应详情

0.33 g (14.4 mmol) of sodium were dissolved in 50 ml of methanol, 3.16 g (12.03 mmol) of 1-butoxy-4-chloro-4,5,5,5-tetrafluoropent-1-en-3-one and 1.27 g (12.03 mmol) of malonamide were added and the mixture was heated under reflux for 7 h. The mixture was concentrated, and 1N hydrochloric acid was then added. The resulting precipitate was filtered off with suction and dried. This gave 380 mg (12% of theory) of a yellowish powder.

1. temperaturethe mixture was heated
2. temperatureunder reflux for 7 h
3. concentrationThe mixture was concentrated
4. addition1N hydrochloric acid was then added
5. filtrationThe resulting precipitate was filtered off with suction
6. customdried