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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 512836Generated: October 26, 2026

6-(Trifluoromethyl)indoline → 1-(1-(6-(1-methyl-1H-pyrazol-4-yl)pyridazin-3-yl)piperidin-4-yl)-6-(trifluoromethyl)indoline

https://huagongshe.com/reaction/512836

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(Trifluoromethyl)indolineHCID 10176437—
Reactant1-(6-(1-methyl-1H-pyrazol-4-yl)pyridazin-3-yl)piperidin-4-oneHCID 89613995—
Product1-(1-(6-(1-methyl-1H-pyrazol-4-yl)pyridazin-3-yl)piperidin-4-yl)-6-(trifluoromethyl)indolineHCID 76314721—

Reaction Steps

The title compound was prepared following the procedure as described in Example 5, STEP 4, reacting 6-trifluoromethylindoline and 1-(6-(1-methyl-1H-pyrazol-4-yl)pyridazin-3-yl)piperidin-4-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09102669B2
Source datasetuspto-grants-2015_08
ORD IDord-778f5a1f3b6c4ba09124dadb61d128ea
Source noteuspto-grants-2015_08