Sulfuric Acid → 6-Bromo-7-methoxyindoline-2,3-dione

Participants

Reaction Steps

A mixture of N-(3-Bromo-2-methoxy-phenyl)-2-hydroxyimino-acetamide (36 g, 0.132 mol), conc.H2SO4 (193 mL) is stirred at 80° C. for 1 hour. After reaction, poured the reaction mixture into ice water (2 L). The mixture is filtered and the solid is dried under vacuum to give the desired product.

Provenance & Evidence