HCID 86702663, compound → HCID 86702664, compound

HRID 513331Notes

Reaction equation

HRID 513331 reaction equation
[C:1]1([C:7](=[O:21])[C:8]#[C:9][CH2:10][CH2:11][CH2:12]/[CH:13]=[CH:14]/[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>ClCCCl>[CH2:12]1[C:13]2=[CH:14][C:15]3[C:16]([C:8]([C:7]([C:1]4[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=4)=[O:21])=[C:9]2[CH2:10][CH2:11]1)=[CH:17][CH:18]=[CH:19][CH:20]=3

Participants

3

Reactant 1

HCID 86702663HCID 86702663, compound

Product 1

HCID 86702664HCID 86702664, compound

Reagents, catalysts & solvents 1

HCID 111,2-DichloroethaneSolvent

Conditions

Temperature
180 °C

Procedure

To a 2-5 mL microwave irradiation vial equipped with a stir bar was added enyne 5e (0.050 g, 0.18 mmol) in DCE (3.0 mL). The reaction was irradiated with stirring at 180° C. for 90 min until complete by TLC. The reaction turned golden in color. The reaction was then transferred to a vial, concentrated under reduced pressure, and dried under vacuum to yield naphthalene 6e as a black oil (0.050 g, quant.).

Workup

  1. customTo a 2-5 mL microwave irradiation
  2. customvial equipped with a stir bar
  3. customThe reaction was irradiated
  4. concentrationconcentrated under reduced pressure
  5. customdried under vacuum

Sources & evidence

ORD record
ord-6312c3a066524cc49c1eb181b81b03e2
Source dataset
uspto-grants-2015_08
Patent number
US09102703B2

Reaction notes

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